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Water: Risk Assessment

National Guidance: Guidance for Assessing Chemical Contaminant Data for Use In Fish Advisories - Volume 2

Volume 2: Risk Assessment and Fish Consumption Limits - Third Edition

November 2000; EPA 823-B-00-008

Download the complete guidance: Volume 2: Risk Assessment and Fish Consumption Limits (PDF) (383 pp, 1.2MB; About PDF).

  1. Introduction
  2. Risk Assessment Methods
    • Introduction
    • Hazard Identification
    • Dose-Response Assessment
    • Exposure Assessment
    • Risk Characterization
    • Summarizing Risk Data
  3. Development and Use of Risk-Based Consumption Limits
    • Overview and Section Organization
    • Equations Used to Develop Risk-Based Consumption Limits
    • Default and Alternative Values for Calculating Consumption Limits
    • Modification of Consumption Limits for a Single Contaminant in a Multispecies Diet
    • Modification of Consumption Limits for Multiple Contaminant Exposures
  4. Risk-Based Consumption Limit Tables
    • Overview & Section Organization
    • Consumption Limit Tables
  5. Toxicological Profile Summaries for Target Analytes
    • Introduction
    • Metals
    • Organochlorine Pesticides
    • Organophosphate Pesticides
    • Chlorophenoxy Herbicides
    • Polycyclic Aromatic Hydrocarbons (PAHs)
    • Polychlorinated Biphenyls (PCBs)
    • Dioxins
  6. Mapping Tools for Risk Assessment and Risk Management
  7. Literature Cited (48K)


  • A—Reviewers of First Edition of Guidance Document
  • B—Population Exposure Assessment & Consumption Patterns and Surveys
  • C—Dose Modification Due to Food Preparation and Cooking
  • D—Guidance for Risk Characterization
  • E—Additional Developmental toxicity Issues
  • F—Summary of Limits of Detection for the Recommended Target Analytes

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